Small bowel malignancy is still a rare case as a cause of gastrointestinal bleeding.The symptoms of small bowel malignancy are not specific.One of the low profile barn door kit symptoms is obscure gastrointestinal bleeding.Obscure gastrointestinal bleeding (OGIB) is defined as recurrent or persistent gastrointestinal bleeding when the result esopha
The Principle Based Explanations Are Not Extinct in Cognitive Science: The Case of the Basic Level Effects
There is a tendency in recent philosophy of cognitive science, best seen in the writings of Bechtel et al., to overstate the significance of mechanistic explanations and to neglect the explanatory role of principles.This paper is a plea for restoring the balance.It draws attention to the search for explaining the so-called basic level effects, one
A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation.
Activation-induced cytidine deaminase (AID) is believed to initiate somatic hypermutation (SHM) by deamination of deoxycytidines to deoxyuridines within the immunoglobulin variable regions genes.The deaminated bases can subsequently be replicated over, processed by base excision repair or mismatch repair, leading to introduction of different types